How to Predict the Major Organic Product of the Following Reaction

How to Predict the Major Organic Product of the Following Reaction

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Introduction

In order to predict the major organic product of a reaction, you’ll need to be familiar with the following:
-Types of reactions (E1, E2, SN1, SN2)
-Reaction conditions (concentration, temperature, solvent)
-Mechanism of the reaction
-Stereochemistry of the products

Methods

There are several ways to predict the major organic product of a reaction. The most common method is to use the reactivity series. The reactivity series is a list of elements in order of reactivity. The most reactive element is at the top of the list and the least reactive element is at the bottom.

Determining the Major Product

In organic chemistry, there are numerous variations of a given reaction that can lead to different products. To determine the most likely product of a reaction, chemists use a variety of methods, including:
-Molecular orbitals
-Thermodynamics
-Kinetics
-NMR spectroscopy

Determining the Reaction Conditions

The starting materials, products, and physical conditions of a chemical reaction are called the reaction’s “conditions.” By knowing the conditions of a reaction, chemists can sometimes predict the reaction’s outcome. Temperatures, pressures, amounts of reactants and products, and the presence or absence of catalysts are all examples of conditions that can affect a reaction.

Results

The major organic product of the following reaction is

Major Product

The major product of the following reaction is predicted to be compound A.

Reaction Conditions

The following reaction conditions predict the major organic product of the given reaction.
-If the substrate has a tertiary carbon, then E2 elimination is favored over E1 elimination.
-If the substrate has a secondary carbon, then E1 elimination is favored over E2 elimination.
-If the substrate has a primary carbon, then both E1 and E2 eliminations are possible, but E1 is favored.

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Discussion

In organic chemistry, there are certain rules that can be followed in order to predict the major organic product of a given reaction. The following steps can be used in order to predict the major organic product:

1) Determine which reactant is more substituted.
2) Choose the more substituted product as the major product.
3) If both reactants are equally substituted, then choose the product with the better leave-behind group.
4) If both products are equally substituted, then choose the product with the better incoming group.

Conclusion

In conclusion, the major organic product of the following reaction is the product with the lowest energy.

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